Opened Vial: Where to Find Your Discard-By Date
Your vial's discard-by date is printed on its label or comes from your pharmacist. On the question "does compounded semaglutide expire after 28 days," FDA says a compounded GLP-1 product in a multi-dose vial should be discarded within 28 days after first use, even if medication remains1.
Count the days
Enter the date and the number of days to see the date.
You type the number of days. There is no default. FDA's page on unapproved GLP-1 drugs says a compounded vial is discarded within 28 days after first use, even if medication remains (page current as of 10/01/2026). Source: FDA: concerns with unapproved GLP-1 drugs (opens in a new tab).
This counts days on a calendar. It does not decide how long a product can be used. Follow your label and ask your pharmacist. Not medical advice.
What FDA says about multi-dose vials
As of 10/01/2026, FDA says multi-dose sterile vials generally should be used within 28 days after first use1. For a compounded GLP-1 product in a multi-dose vial, that holds even if medication remains1. Newer wording shows up in the dated list of FDA alerts.
As of 03/26/2024, CDC says an opened multi-dose vial should be dated and discarded within 28 days, unless the manufacturer states another date2. The beyond-use date should not go past the manufacturer's original expiration date2. If your label shows both dates, write each one down as printed.
What labels print for their own products
In the 2026 label versions on DailyMed, approved products print their own in-use wording3456. It varies by product. Copy the exact words for yours into your notes.
If your label has no date
As of 12/11/2023, USP says the preparer assigns the beyond-use date for a compounded sterile preparation7. We found no official source that sets one period for every product. So this page gives none. For the label places to check, see where to find your storage and expiry dates.
Write down exactly what you were told and who told you.
Write the date down
Use Save as a vial, with the date from your label in the peptide tracker. You can also check how long a vial lasts at your schedule or Print the pharmacist questions (free PDF).
What to ask your pharmacist
As of 07/26/2024, FDA says patients should ask how to measure the intended amount when labels use milliliters, milligrams or units8. These are questions only.
- What is the strength on the label per container and per mL, and can you show me how to read a vial label on this one?
- Is the amount for each use written in mg, mL, or units? Can you write all 3 for my prescribed amount with mg, mcg and units explained in mind?
- Which syringe size goes with this product, and can you show me how to read an insulin syringe on the one I have?
- What is the discard-by date once I first use this vial, and where is it printed?
- Your instructions give a number of days, and FDA mentions 28 days1. Which one applies to my vial?
- Do I need a new syringe for every use of this vial?
- Who compounded this product, and how do I reach them with questions about the label or instructions?
- What should I do if a shipment arrives warm or without enough cold packs?
- Is this the manufacturer's product or a compounded one?
- Who do I call with questions, and how do I report a problem?
Questions
Does compounded semaglutide expire after 28 days?
As of 10/01/2026, FDA says a compounded GLP-1 product in a multi-dose vial should be discarded within 28 days after first use1. The date for your own vial is the one on its label or from your pharmacist.
How long after mixing peptides can you use them?
We found no official source that sets one period for all peptide products, so this page gives none. USP says the preparer assigns the beyond-use date for a compounded sterile preparation7.
Read this first. Information only, not medical advice. This site does not recommend amounts. Talk to your prescriber or pharmacist about your own situation. 18+. Questions about your medicine, symptoms or a reaction? Contact your clinician or pharmacist. In an emergency, call 911. Poison Help: 1-800-222-1222.
Editorial review against cited sources. Last checked Oct 12, 2026.
Sources
- FDA: concerns with unapproved GLP-1 drugs (vials) (opens in a new tab), U.S. Food and Drug Administration. Content current as of 10/01/2026.
- CDC: injection practices guidance (opens in a new tab), Centers for Disease Control and Prevention (CDC). Page dated 03/26/2024.
- DailyMed: Zepbound label (opens in a new tab), FDA-reviewed label posted on DailyMed (U.S. National Library of Medicine), labeler Eli Lilly and Company. SPL version 40, label effective 2026-08-28 (Prescribing Information revised 08/2026); DailyMed listing posted Sep 02, 2026.
- DailyMed: Mounjaro label (opens in a new tab), FDA-reviewed label posted on DailyMed (U.S. National Library of Medicine), labeler Eli Lilly and Company. SPL version 40, label effective 2026-08-27 (Prescribing Information revised August 2026); DailyMed listing posted Sep 02, 2026.
- DailyMed: Ozempic label (opens in a new tab), FDA-reviewed label posted on DailyMed (U.S. National Library of Medicine), labeler Novo Nordisk. SPL version 20, label effective 2026-06-01 (Prescribing Information revised June 2026); DailyMed listing posted Jun 10, 2026.
- DailyMed: Wegovy label (opens in a new tab), FDA-reviewed label posted on DailyMed (U.S. National Library of Medicine), labeler Novo Nordisk. SPL version 19, label effective 2026-06-18 (Medication Guide revised 06/2026); DailyMed listing posted Jun 30, 2026.
- USP: <797> FAQs (opens in a new tab), United States Pharmacopeia (USP). Updated 12/11/2023.
- FDA alert on dosing errors with compounded injectables (opens in a new tab), U.S. Food and Drug Administration. Content current as of 07/26/2024.